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PCOS and I can't lose weight for the life of me — what ACTUALLY worked for you?

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PC
pcosJourney34
member Original Poster
#1

34F, diagnosed PCOS at 22. Have tried, at various times: keto (4 months, worked then plateaued), intermittent fasting 16:8 (worked for 6 weeks then plateau), inositol (took for a year, mild improvement in cycles, nothing on scale), metformin (briefly, GI side effects were brutal), a strict plant-based diet (lost 8 lbs then regained), low-carb non-keto, calorie cycling.

I'm tired. The "just eat less move more" advice doesn't account for PCOS-specific insulin resistance. The "keto fixes everything" advice stopped working for me. Looking for REAL stories from PCOS women who actually made progress. What worked? What was the one thing that finally moved the needle?

Best Answer
IN
insulinSensitive
member
#2

PCOS here. 42 lbs down over 18 months and cycles regular for the first time in my adult life. The thing that finally worked: strength training 4x/week + walking 10k+ steps daily. Not a diet change. Cannot overstate how much muscle mass matters for insulin sensitivity in PCOS. Everything else is a rounding error compared to that.

CY
cystersQueen
member
#3

Honestly, sleep. I was sleeping 5-6 hrs for years thinking "everyone is tired." Got serious about 7.5+ hrs, got a CPAP after a sleep study (yes really, a lot of PCOS women have undiagnosed apnea), and lost 22 lbs in 8 months without changing my diet.

HE
healthyHannah
member
#4

Inositol + NAC + berberine was my stack. 4g myo-inositol, 2g NAC, 500mg berberine (ONLY with doctor supervision since it interacts with stuff). Lab insulin dropped from 18 to 9 in 6 months. Scale followed.

YO
yogaLisa
moderator
Mindful Eating Coach
#5

Stopped counting calories entirely. I was chronically underfed which was spiking cortisol and making PCOS worse. Started eating to satiety of nutrient-dense foods, aiming for 100g+ protein, and just... moved more. Lost 28 lbs. Counterintuitive but PCOS responds badly to aggressive deficits.

FI
fitnessmom42
moderator
Macro Wizard
#6

Got my thyroid checked for the tenth time and finally got a doctor who ran ALL the markers (not just TSH — free T3, free T4, reverse T3, TPO antibodies). Hashimoto's was comorbid with my PCOS and nobody had caught it. Treated the thyroid, scale moved. Worth ruling out if you haven't.

FA
fatLossPhD
member
#7

Evidence summary: the research on PCOS nutrition has converged over the last few years. The pattern that works for most PCOS women is moderate-carb (40-45% of calories from quality carb sources), high-fiber (35g+), high-protein (1.2-1.6 g/kg), and critically — resistance training. Keto works for some PCOS phenotypes, doesn't for others. Strength training works for essentially all of them.

PC
pcosJourney34
member
#8

Okay so the pattern I'm seeing: everyone who made real progress lifted weights. I don't lift. I do Peloton and yoga. Maybe that's the variable I haven't changed yet. Signing up for a gym this week.

IN
insulinSensitive
member
#9

@pcosJourney34 that's it. Get under a barbell or pick up heavy dumbbells at least 3x/week. You don't have to be fancy. Squats, deadlifts, rows, presses. Progressively heavier. Six months in you'll be a different person metabolically.

BO
bodyRecompBro
member
#10

Not PCOS but want to add: stop apologizing for not doing it "right" before. PCOS is a moving target and most advice you've been given was wrong for YOUR phenotype. This isn't a willpower story, it's a mismatch-of-intervention story. You're closer than you think.

CY
cystersQueen
member
#11

One more: track cycles alongside weight. When my cycle normalized, the scale moved down noticeably (was retaining water for weeks because of estrogen dominance). The improvements aren't linear, they're cycle-phased.

PC
pcosJourney34
member
#12

3-month update: started lifting 3x/week (StrongLifts 5x5). Down 11 lbs. Energy through the roof. Cycles shortened from 52 days to 34 days (still irregular but closer to normal). Feel like a different person. Wish I'd done this 10 years ago. Thank you all.

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